01x01 - Watson

[bunniefuu]

[g*nsh*t]

[PANTING]

Holmes!

[g*nsh*t]

Sherlock!

[g*nsh*t]

[GASPS]

[GASPS]

Holmes!

You've had a knock on the head, guv.

WATSON: Sherlock! Holmes!

Rest.

Uh...

[RHYTHMIC BEEPING]

I... I can't remember your name.

Shinwell Johnson.

What a ridiculous name.

[LAUGHS]

So you've said, guv.

You've had a traumatic brain injury.

I should go get your doctors.

Wait.

What happened to Holmes?

I've been praying

to whatever God would hear me

that you'll wake up.

And I've been dreading what
I'd have to say when you did.

Three men went over the waterfall.

Yourself, Mr. Holmes and
the man we'd been chasing.

- James Moriarty.
- One survived.

We've lost him, guv.
We've lost Mr. Holmes.

I was trying to help him, Shinwell.

I went into the water
after to go get him.

- And I-I-I was close, and I thought...
- Right.

- I thought I...
- Yeah. I know.

You were the best friend
Mr. Holmes ever had.

So don't you go punishing
yourself 'cause I won't have it.

We will take time later,

and we will remember the man properly.

But they're gonna want to have
a look inside your thick skull

now you're up.

Hey.

Did you know that he was loaded?

Holmes lived in a two-bedroom
flat on Baker Street.

He might have been quiet about it...

... but Holmes had
the bees and the honey

to look after us both.

Seems the man had a vision.

Vision of you practicing medicine again.

He's funded a clinic for you to run.

You hire your choice of medics.

There'll even be a certain...

former hard man around

to help you look after the place.

Former?

You're in Sherlock's will?

He's paying me

to be your aide.

[CHUCKLES]

Here.

You're going home, guv.

NURSE: There she is.

- Look how beautiful.
- [HEART BEATING ON DOPPLER]

Huh. [INHALES SHARPLY]

How are you, darling?

Just haven't really been... sleeping.

I bet people say, "You need to
relax," when you tell them that?

[INHALES AND EXHALES HEAVILY]

[FETAL HEARTBEAT DISTORTING]

[GASPS]

Are you okay, hon?

Did you see that?

[VOICE DISTORTING]: What is it, honey?

[GROANS] I...

- I have to... I'm good. I have to...
- Erika?

[GRUNTING]

Are you all right?

[VOICE DISTORTING]: Miss Filipello?

[GASPS] [CAR HORN BLARING]

[TIRES SCREECH]

[SCREAMS]

- Don't move. I'm gonna call for help.
- Ambulance.

Call an ambulance!

[ELEVATOR BELL DINGS]

♪ ♪

- It's past 8:00.
- Good morning, Dr. Derian.

It's Tuesday, September 24.

My name remains John Hamish Watson.

It would be my pleasure to
repeat any ten words you'd like.

You should let me ask the questions

- before you answer them.
- Good morning, Shinwell.

Good morning, Dr. Watson.

Your young doctors need tending.

Yes, I've noticed.

You should let me ask the questions

before you answer them.



Watson, we seriously
need another centrifuge

if you want us to log this many genomes.

It's the best lab in
the country, Dr. Lubbock.

I'm sure you'll figure it out.

Good morning, Dr. Croft.

We've got 200 patient
applications coming in every day.

Can we see a patient from Malta?

Of course we can. Malta's an island.

Good morning, Dr. Croft.

I told him island
populations are fascinating.

Well, keep at it. Your
brother can be stubborn.

WATSON: I understand that, as
my neurologist, you're obligated

to track my recovery, but I'm fine.

I've been fine for months.

- How are the headaches?
- Manageable.

Okay, any hyperventilation, sweating?

Nope.

What about the weeks
leading up to your injury?

Still a blank?

Mostly.

I'm starting to...
remember things about him.

"Him"? James Moriarty?

I can see his hands.

He has syndactyly.

His second and third fingers are fused.

Almost like they make
the shape... of an "M."

What?

An archvillain named Moriarty

whose hands make the shape of an "M"?

That sounds fictional.

- Did you ever see his face?
- I don't know.

Shinwell.

I have a referral for you.

I don't like this.

Being your neurologist and
working for you at the clinic.

I trained under Dr.
Ishikato. She's excellent.

Oh, that's very nice, but I already have

the best neurologist in the
state... you, Dr. Derian.

Cool flattery.

You're still exploiting an
unbalanced power dynamic.

I get nervous when young people
point words like that at me.

Get another neurologist...
problem fixed.

SHINWELL: Dr. Morstan
was asking for you on six.

WATSON: She has a scaphoid fracture

and a compound break to the tibia.

It's a typical post-accident trauma.

- Why are you filming her?
- Scroll ahead.

She never fell asleep.

We admitted her two days ago,

and she's been awake since then.

She says it's been seven days total.

Her name is Erika Filipello.

There's a family history
of fatal familial insomnia.

Oh, see, that's a snake pit.

There's no test. The
only way to diagnose it is

to observe the progression
of her symptoms.

She needs someone with your expertise.

Are you asking as the medical director?

In what other capacity
would I be asking?

Well, it's fair to
say that I owe you one.

I mean, I did leave home for six months.

Couldn't call, couldn't write.

I showed up at the
bottom of a waterfall.

- I forgive you for that, John.
- Yes.

You forgave me all the
way to my own apartment.

I'm asking as the medical director.

Got it. Okay. Well,
Mary, if she has FFI,

she'll stay awake until
the proteins in her brain

hollow out the thalamus, and
then, unfortunately, she'll die.

And she'll require medical
care the whole time.

She's already having hallucinations.

That's how she wound up here.

- Erika says her father died of FFI in 2012.
- Oh, don't tell me.

I take my own histories.
It's the only way

- to avoid anchor bias and start fresh.
- And start fresh.

- Yeah, so give me the morning with her.
- Thank you.

I'm, uh, finally remodeling the garage.

I need you to get your
boxes out of there.

Oh, you know what? I haven't
gotten a storage unit yet.

Is that by design,
John? Search your soul.

The boxes are not a beach head.

I'm on it.

Okay.

You've been rehabbing for six months.

The clinic's been open for two.

I'll check back in a bit.

[INDISTINCT ANNOUNCEMENT OVER P.A.]

Good morning, Erika. I'm Dr. Watson.

- I'm consulting on your case.
- You're the specialist?

Yes, I'm a clinical
geneticist and internist.

I watched my father
die of FFI, Dr. Watson.

It took my grandfather before that,

and I know it's going to k*ll me, too.

I don't think we're there yet.

When someone starts
showing symptoms of FFI,

they're typically dead
within three to eight months.

And don't tell me that I'm wrong,

because it runs in my family,

and I've been worried
about it my whole life.

We have a job to do here.

I'm... I'm five and
a half months pregnant,

and I know...

I know I'm going to die.

I don't want this baby to die, too.

[BREATHING SHAKILY]

You're gonna manage my symptoms.

Keep me alive until I can...

deliver her... safely.

♪ ♪

You four are the smartest
doctors I could find.

What does this family history tell us?

[SOUTHERN ACCENT]: A presumptive
diagnosis of fatal familial insomnia,

which you've highlighted in red,

shows up in every
generation of Erika's family.

But the pattern's unusual.

Her father's one of six siblings,

but he's the only one to contract FFI.

Are you nodding 'cause you
agree with me, or are you trying

to think of a way to
make fun of my accent?

Bless your heart, Dr. Lubbock.

[SOUTHERN ACCENT]: I would never.

FFI is autosomal dominant.

You can only inherit the
gene from an affected parent.

But if they had it, you
got a straight 50-50 shot.

So, Erika's father had five siblings,

each with a 50% chance of getting FFI.

You flip a coin once,

comes up heads for FFI.

What are the odds that you
flip a coin five more times

and it comes up tails?

One-half to the power of five.

A little better than three percent.

Are you saying you don't
think Erika's father had FFI?

Whenever we take on a case,
we examine every assumption.

We eliminate the impossible.

Whatever remains, however improbable...

- However improbable...
- Must be the truth.

WATSON: ... must be the truth.

Erika's father took his own life
after the onset of his symptoms.

He thought he inherited FFI.
He didn't want to die like that.

His father died from a car accident.

There's no conclusive evidence
that Erika's father had FFI.

And if he didn't have
it, she can't have it.

Except that she reports
no sleep for seven days.

WATSON: Which could very well mean

that she has fatal familial insomnia

or could mean that she's
trapped in a cycle of anxiety.

ADAM: Anxiety?

For seven nights in a row?

STEPHENS: The mind is
a powerful thing, Adam.

They've done studies and everything.

WATSON: You know, it
would've been easier

to work with you two before
Adam started dating your ex.

He broke up with her years ago.

A year ago.

You still gave me your blessing.

WATSON: Let's save the
tension for Thanksgiving.

I'd like to offer Erika Filipello

something besides a slow death.

We need to widen our differential,

see if she has something other than FFI.

Adam and Stephen... s.

Stephens. My name is Stephens.

WATSON: Yeah, I don't like it.

Sounds like there's more than
one person named Stephen here.

Crofts, go to Erika's house.
Dig into her family history,

see if you can bring us
back something interesting.

Sasha, Ingrid, what tests
would you suggest we run?

An MRI.

Blood work to check
for a B12 deficiency.

An FDG-PET to test for a decrease

in glucose utilization in the thalamus.

Off you go.

MRS. FILIPELLO: My daughter had a
set of identical twins in her class.

Zoey wore pink. Emma wore purple.

Maybe the two of yinz can
do something like that?

Thank you, ma'am. We'll look into that.

When your husband got sick,
do you recall if a doctor

ever treated it as FFI?

Paul hated doctors.

[WHEEZES] I think he went
twice before he just gave up.

ADAM: It would also
help to track any changes

to your daughter's diet, her lifestyle.

Are we talking about Paul,
or are we talking about Erika?

Uh, we threw Erika that pregnancy party.

Let's stay focused on
Erika's father for the moment.

What was unusual about the party?

Um, my mom and I made her
a plate of our deviled eggs.

Erika ate the whole
thing. She had cravings.

Oh. You're not Erika's sister?

- I'm her cousin.
- STEPHENS: If we can get the names

- of those doctors...
- Does Erika have a sensitivity to eggs?

- No.
- I'm sorry, Mrs. Filipello.

My brother's a functional
medicine doctor.

He thinks everything goes
back to an egg sensitivity.

[MRS. FILIPELLO CRIES]

[MRS. FILIPELLO WHEEZES]

I'm sorry, ma'am. We are...

we are doing everything
we can to help Erika.

Anything we might learn
about her father...

contact information for his doctors,

old pictures, videos...

anything might help.

There's no harm in being thorough.

There's potential harm in wasting time.

Why go to medical school if
everything is a folk remedy?

Why not get a certificate in...

I don't know, Reiki massage
or angel readings or the moon?

Certificate in the moon.

- Huh.
- [MOCKING]: "Huh."

PAUL [ON VIDEO]: So, down at that end...

- Huh.
- PAUL: It was this end.

It was this end where I
scored the winning goal.

These were all recorded within
a year of Paul Filipello's death.

He looks like he's walking like a...

A chicken.

Dystonic posture.

Also known as a c*ck-walk.

Was Erika's father a steelworker?

How'd you know that?

WATSON: The c*ck-walk gait
is consistent with manganism,

a variety of heavy metal poisoning

seen most commonly in those
with consistent exposure

to arc welding equipment.

Dr. Derian,

tell us a story

about what might have happened here.

INGRID: Paul Filipello gets sick.

Some of the symptoms
of manganism overlap

with symptoms of FFI.

And worrying that he had FFI
interrupted his sleep patterns.

When none of his doctors could
tell him what's wrong with him,

Paul decides he has FFI

- and kills himself.
- Compelling narrative.

Tracks with what I'm observing.

Let's agree amongst ourselves
that Erika Filipello's father

didn't have FFI.
Therefore, neither does she.

The chances are just too remote.

I'm willing to exclude the diagnosis.

- But where does that leave us?
- STEPHENS: We still can't be sure

if she's suffering from anxiety

or if there's an underlying condition.

The only way to prove that
she doesn't have the disease

is to help her fall
asleep and stay asleep.

And if you're right, the
fact that she believes

that she has it is exactly
what's keeping her awake.

WATSON: There is...

one thing we can do for her.

[HARD ROCK MUSIC PLAYING]:
♪ The enemy is everywhere ♪

♪ No one seems to be aware or care... ♪

It's an interesting
choice for 10:00 p.m.

Not like I'm gonna sleep.

Here.

You pick something.

[SONG STOPS]

["AVRIL 14TH" BY APHEX TWIN PLAYING]

So, I have some news.

None of this has been written up

in any medical journals yet.

And very few people know
what I'm about to tell you.

Dr. Morstan.

- Adam, right?
- Yeah.

I'm here to check up on Erika Filipello.

WATSON: Some research colleagues of mine

have developed a test for FFI.

It's as close to definitive
as these things get.

I rushed your labs to her.

- Oh, my God.
- Erika, it's good news.

You tested negative.

You do not have FFI.

[EXHALES]

You may be sick with something else.

And if you are, we will
find out what that is.

See if you can get some sleep, okay?

Dr. Watson.

Would you stay with me a little longer?

[ELEVATOR BELL DINGS]

WATSON: I left my life behind to...

go solve mysteries in London.

[BOTH CHUCKLE]

Trust me, I wish that was a joke.

When I got back from
the w*r, I struggled.

"The story of our lives
is written inside of us

before we're ever born."

My first genetics professor said that.

It's a hard way to live.

Nothing really surprises you.

Then I met someone in London who...

... turned all of that on its head.

We became partners.
We were close friends.

My wife...

... she saw that I...

needed something, whatever it was

that I was getting out
of working with Holmes.

And in the end,

when the call came from Holmes,

I picked him over Mary.

Of course, I didn't see it that way.

I just thought, "One last case."

But everything has its
breaking point, and...

unfortunately, I found ours.

And...

... when I was in that water...

... I thought I was about to die,

my last thought

before going over that fall was...

... I'd never get a chance
to put it all back together.

So...

♪ ♪

So you heard all that?

Lying to patients is not an
ethical form of treatment.

Not in my hospital.

That's what you want to talk about?

- Yes.
- Look, I am sorry about almost everything,

but I am not sorry about that.

Look at the patient.

I helped her.

[BIRDS CHIRPING]

Oh. Morning, darling. How'd you sleep?

Who is that?

Dr. Lubbock.

We've been taking shifts.

[PANTING]

- Whoa, whoa. What's wrong?
- I... I...

I can't see you.

I-I can't see anything.

[BREATHING HEAVILY]

- WATSON: You're blind.
- [GASPS]

I could've told you that.

I needed you to show me.

Dr. Watson,

what's happening to me?

It's a mystery, Erika.

You're a mystery.

I want you to do something for me.

It's the last thing you're
gonna want to do, but...

try it anyway.

Can you smile for me?

You were married once.

You know never to tell a woman to smile.

Not even if her life depends on it?

[HISSES, GROANING]

It hurts.

The sores around the
corner of your mouth...

you have a condition
called angular cheilitis.

Got worse overnight.

What does that mean?

SASHA: Is that...

yeast?

Erika Filipello has a yeast infection.

Around her mouth?

A fungal infection shouldn't
cause angular cheilitis in someone

with a healthy and intact immune system.

We may have a narrow window to act here.

Act on what?

She's got a nonspecific
deficiency in her T and B cells.

The tests,

this infection...

it's consistent with severe
combined immunodeficiency.

SCID? "Boy in the bubble" syndrome?

We have to replace her faulty
immune system with a new one.

INGRID: You want to give her

- a bone marrow transplant?
- This is textbook overtreatment.

Hire an immunologist,
get an immunodeficiency.

- [SCOFFS]
- A bone marrow transplant has lifelong side effects.

Erika Filipello was fine a week ago.

She's also pregnant.

If I'm right and we don't
intervene, they'll both die.

She is 23 weeks pregnant.

- The fetus is viable.
- Barely. Maybe.

SASHA: If we deliver the baby

and then we do the transplant,

it has a small chance of surviving.

- AUTOMATED VOICE: Caution.
- WATSON: Pardon me.

Proceed with caution.

Anyone else worry that LabGuardian 1881

is gonna turn sentient and k*ll us all?

His name is Clyde, but we need
to find a bone marrow match

before a transplant is even viable.

Erika's records mention a brother.

STEPHENS: Damon Filipello.

He's been in and out of rehabs

since their father died.

No one knows where he is.

Well, that's our best
shot at a match by far.

We need to find him.

Can Gregson help with that?

Well, he does work at Scotland Yard.

Uh... [CHUCKLES SOFTLY]

You act like you never tracked
down a missing person before.

We're doctors, not detectives.

WATSON: Well, that's too bad,

because right now, your
patient needs a detective.

I'll work this on my end.

You guys see what you can do
with finding Damon Filipello.

Anybody know any bounty hunters?

♪ ♪

[LAUGHS] Oh, it's a good bit
of crack, this, innit, eh?

Running down a fugitive.

Yeah, you miss it?

You miss him?

The world's less... I don't know, bright

without Sherlock Holmes in it.

I reformed myself 'cause of Holmes.

Shame. Yeah.

I'll always mourn the man.

But I'm grateful you're still here.

I suppose you could say
you're my Sherlock now.

You know, I do miss
that moment, Shinwell.

That moment when you helped
Holmes get to an answer

and the whole world
just snapped into place.

Mm.

Nothing like it.

You know, I actually
heard the man say "eureka."

You know, he was the
only person in the world

who could say that word
and not sound like an idiot.

I don't know about that, guv.

Might be one other.

♪ ♪

I haven't heard from
Damon in a long time.

I was hoping not to hear from him.

Damon's been lying to us for so long.

Would you excuse me? I'd
love to talk to Autumn.

Sure.

Congratulations.

Not easy to get clean from heroin.

Saw that recovery tattoo.

It's good placement. It covers up

the scars from your track marks.

So?

I worked hard for my time.
No one's gonna shame me.

Oh, that's not something I'd do.

I'm here because you and your
cousin Damon had a common vice.

And I didn't want to embarrass you

in front of your aunt, but if
you have ever used with him,

if you know anything at all
that would help me find him,

I'd appreciate it.

So would Erika.

If you change your mind.

Christopher Maude. Damon had a fake I.D.

with the name "Christopher Maude" on it.

Whenever he was up to something sketch,

that's the alias he'd use.

SASHA: All right, thanks so much.

Please call if you hear anything.

That's all the rehabs.

Any luck with the hospitals?

Is anyone else wondering why
we went to medical school?

We work for a man who'd
rather text Scotland Yard

than tell us about a case.

His closest confidant is a man

named Shinwell Johnson, who, by the way,

has definitely k*lled people before.

You chose this fellowship

because it's too good
to pass up. We all did.

But why did he pick us?

ADAM: You seriously don't know?

Watson sees the whole world as
an experiment in genetic medicine.

We're just a part of it.

Stephens and I have identical
DNA, same background.

We even dated the same partner.

We are a living test of
nature versus nurture.

Sasha's a variation on the same theme.

You were born in China,

presumably in a poor and rural area,

given prevailing adoption practices.

You were adopted into the
wealthiest suburb in Dallas, Texas.

Watson wants to see how that turns out.

I worked my a*s off in medical school.

Hmm. I hope you don't
think that impressed Watson.

We're not Sherlock Holmes,

whoever that was.

What about me?

Honestly, I don't know.

You, Ingrid...

you're a mystery.

- SHINWELL: Welcome home, guv.
- WATSON: Shinwell.

Evening, everyone.
This is Damon Filipello.

Let's, uh, book that O.R. and get ready

for the bone marrow harvest.

Right this way.

It's gonna be a harmless procedure.

INGRID: How did you find him?

Inspector Gregson worked a joint
task force with the local police.

An officer there had a
confidential informant

who occasionally referred
to another hustler

as "Christopher Maude."

A stakeout ensued, and here we are.

Damon, you can just wait right in here.

Dr. Derian will get
you whatever you need.

[PHONE BUZZING]

"A stakeout ensued"?

That's a serious outlier of a sentence.

Yes, yes, outliers. Outliers...

are where life happens, Dr. Derian.

[PHONE BUZZING]

Hello?

AUTUMN: Dr. Watson, it's Autumn Franco,

Erika's cousin.

Autumn, is everything okay?

What's wrong?

I'm sick.

I'm sick, like Erika.

What is happening to me?

We're sick with the same thing?

Did I catch it from Erika?

I can't tell you that yet, but
we have to act like you did.

- [PHONE CHIMING, BUZZING]
- We've been through your houses,

and now I have a team
going through everything

you've both thrown away.

[CAMERA CLICKS]

[PHONE WHOOSHING, BUZZING]

Of course, you're cousins,
so we have to consider

genetic causes, too.

[PHONE CHIMES, BUZZES]

WATSON: I want to focus on the times

you were together over the past month.

You mentioned a pregnancy party.

Is there anything else?

No, no. Just the party.

[PHONE CHIMES, BUZZES]

[PHONE CHIMES, BUZZES]

You're thinking biotinidase
deficiency, correct?

ADAM: Neither of them
can recycle biotin.

The avidin from the raw eggs binds

with what little biotin they have.

If I'm right, they take a supplement,

and they both get better.

That is a good idea,
but it's also incorrect.

Biotinidase deficiency
can only be inherited

if both parents are carriers.

Erika and Autumn are maternal cousins.

They're not sisters. They can't...

Can't both have it.

[PHONE BUZZING]

Two dead birds.

Are you all right, Dr. Watson?

Erika, do you have a pet cat?

Erika and Autumn have a
form of salmonella poisoning.

Typically shows up in cats
who hunt birds carrying

the salmonella typhimurium bacteria.

SASHA: Watson?

Stephen... s.

Stephens. Give us a lesson
in infectious diseases.

STEPHENS: Songbird fever
does show up in humans.

Usually people who handle
birds k*lled by their pet cats.

It tracks. It's Erika's
cat. She got sick first.

- Then Autumn started helping at Erika's place.
- All right.

Test them both for the bacteria.
If it comes up positive,

put 'em on antibiotics right away.

INGRID: They last about


The incidents.

It's called paroxysmal
sympathetic hyperactivity.

It's a side effect of
traumatic brain injuries.

This gets worse with time, not better,

which is probably why you
didn't tell me about it.

Is there anything else?

Yes. You're fired.

I can't treat a patient who
hides their symptoms from me.

Why do I work here?

Adam and Stephens are
twins. Sasha's adopted.

If this is an experiment,
how do I fit into it?

There's no experiment.

You're a very capable physician.

Everything all right, guv?

WATSON: Right as rain, Shinwell.

Right as rain.

You get those scrips I wrote for you?

Made my share of bargains,

legal and otherwise.

This one here...

I don't know where it falls.

These aren't controlled
substances, Shinwell.

Medications have off-label uses.

SHINWELL: Well, that just sounds like

you're experimenting on yourself.

I help myself get better
so I can help other people

get better. It's a straight line.

If you're uncomfortable
with that, just let me know.

[THUNDER RUMBLING]

MARY: You slept here?

Probably just as well.

The storm has half the bridges closed.

John, the test results came back.

Autumn Franco has songbird fever.

Well, um...

... just get them some antibiotics.

Autumn Franco has it.

Erika doesn't.

- Doesn't make any sense.
- I'm sorry.

There's an underlying condition.

We also have a more pressing issue.

They're dying. What could
be more pressing than that?

We already started
Autumn on antibiotics.

This strain of songbird
fever... it's resistant.

Autumn developed septicemia.
It's a matter of hours

before she goes into septic shock.

- Where are you going?
- Where Holmes went when he got stuck.

To the scene of the crime.

So you're just gonna...

[SNIFFLES] ... look at us?

ERIKA: You're out of ideas,

aren't you?

I want to deliver my baby.

Today.

Please. Before I get too weak.

It's not over yet.

There's something that I'm missing.

[SNIFFLES] We told you everything.

You told me everything you know.

Your faces, your bodies...

everyone's faces and bodies are clues.

Tell us who we are, where we came from

and what's gonna happen to us.

You two don't look especially
similar, but one look,

and I bet you're related.

You both have orbital hypertelorism...

your eyes are widely spaced.

And that could be a coincidence,
but then I see you both have

two-three syndactyly,

and suddenly, we got
two traits in common.

Two-three what? Syndactyly. Webbed toes.

The skin on your second and
third toes never separated.

I assume both of your mothers had it,

since that's how you're related.

Actually, no.

My mother doesn't
have it. My father did.

My mom didn't, either.

Neither of my parents did.

That's impossible.

You can't have syndactyly

if neither one of your parents had it.

But I do.

And they didn't.

WATSON: Neither one of
Autumn Franco's parents

could have possibly passed the mutation

to two-three syndactyly, but
yet she has it anyway. How?

The only explanation is that she's wrong

about who her parents are.

WATSON: Exactly. Erika Filipello's
father had two-three syndactyly.

He passed it down to Erika
and her brother Damon,

and there's no mystery there.

Does anyone notice anything unusual

about Paul Filipello's eyes?

They're widely spaced.

He has a slight case of
orbital hypertelorism.

WATSON: Notice anyone
else with hypertelorism?

INGRID: Erika.

Her brother, of course.

Oh, my God.

Autumn has it, too.

Two-three syndactyly and
orbital hypertelorism,

two traits that flowed down
from Erika to her brother Damon

to Autumn, all from one source.

Wait, you're saying Erika's
father is Autumn's father, too?

Erika and Autumn aren't just cousins.

They're half sisters, too.

Eureka.

Autumn's my sister?

Half sister. Three-quarter siblings.

This is incredible news. If I'm right,

you two share a
mutation to the BTD gene.

It gives the body instructions

for making the enzyme biotinidase.

Unchecked biotinidase
explains all of your symptoms.

- [LAUGHS SOFTLY]
- Now, we still have to treat

Autumn's songbird fever.

Other than that,

all you need is a
ten-dollar biotin supplement,

available at any drugstore.

You'll be able to see again.

You'll carry your baby to term.

I-I'm gonna live?
M-my baby's gonna live?

Yes.

- [GRUNTING SOFTLY]
- Autumn?

Autumn.

[RAPID BEEPING]

Patient is in septic shock.

We need the ultrasound
to find the abscess

- and surgery to cut it out.
- NURSE: Understood, Dr. Watson.

Where's the surgeon?

Where's the surgeon?

The bridges are closed.

- The resident should be here soon.
- Soon?

Soon she'll be dead.

[THUNDER CRASHES]

MARY: Good afternoon, everyone.

This patient has what looked like

multiple abscesses on the ultrasound.

They're around the liver,
and we need to move quickly.

- CASSIE: Dr. Morstan?
- ["RAINBOW" BY KACEY MUSGRAVES PLAYING]

We got your favorite.

Good memory, Cassie.

I haven't operated in four years.

♪ ♪

♪ When it rains, it pours ♪

♪ But you didn't even notice ♪

♪ It ain't raining anymore... ♪

MARY: There she is.

Look how beautiful.

Did we tell you we picked out a name?

Autumn. After her aunt.

I have to get used to
thinking of myself that way.

Get used to thinking of
yourself as a godmother, too.

Seriously? You want to make
this relationship more tangled?

[LAUGHS]

♪ You hold tight to your umbrella... ♪

Just give it a sec.

She'll move.

♪ Trying to tell you ♪

♪ That there's always
been a rainbow... ♪

WATSON: Got an update on Autumn Franco.

The treatment has run its course.

Her songbird fever's gone.

We're gonna be discharging her tomorrow.

So, thank you for everything.

Night, Dr. Watson.

Ingrid.

I hired you because of your résumé.

No, that's the truth.

It was one of the best
CVs I've ever seen.

And down at the bottom, in
the... in the fine print,

said that you played
Lady Macbeth in college.

There was no production of Lady Macbeth

while you were at the
University of Chicago.

You lied.

You have all of the
qualifications in the world,

yet you... you lied anyway.

[LAUGHS SOFTLY]

So, you hired me because
you think I'm a liar?

I hired you because there's
conflict inside of you.

It sounds like you're diagnosing me.

Your every impulse, it pushes you to...

put yourself first,

but you try to be a
decent person anyway.

Maybe I want to see which
side wins in the end.

Or maybe Moriarty gave me
a clinical interest in...

people like you.

We'll set an appointment?

You get one more shot.

Stop making me fight my way in.

♪ Yeah, there's always been a rainbow ♪

♪ Hanging over ♪

♪ Your head ♪

♪ Mm ♪

♪ It'll all be all right. ♪

[SONG ENDS]

Sorry it took so long.

What's in there, anyway?

You could have told me.

I'm not made of glass.

Somebody's been staying here.

You own one car, the second
parking space is free of clutter.

Coat hook on the inside
is completely clear.

A coat hook is never just empty.

Unless somebody cleaned
it off in a hurry.

Is it anyone I know?

You never met her.

You are a better doctor now, John.

Whatever you did over there with Holmes,

it made you better.

I mean, you were always good.

But you learned things
with him. It's like...

you can see into people's
bodies and their souls.

I'm lucky to be around you.

But the old us...

... is never coming back.

And what is the new us?

You think I'm the reason
you survived that fall,

but there's something else.

You have to find it.

♪ ♪

The game's afoot.

We have a new case.

Who wants to amaze us
with their insights?

♪ ♪

[BELL RINGS]

I could sit here all day.

This view.

The city looks so vulnerable.

A fire might sweep down from the north.

Those rivers could rise.

Who knows?

A germ may even write its
name into history here.

How would you grant this place

the mercy of nonexistence, Shinwell?

You know, I'm not
really one for big ideas.

Professor Moriarty, I presume.

I was expecting someone...

different.

Here you go.

The samples you wanted.

I'm watching.

Always and everywhere.

[SHUDDERING]

♪ ♪